Until recently the factors responsible for peptic ulcers remained unclear; a stressful lifestyle and rich diet commonly were blamed. Evidence now indicates that infection with the bacterium Helicobacter pylori and long- term use of nonsteroidal anti- inflammatory drugs (NSAIDs) are the two major causes of peptic ulcer. Between 1. 0 and 1. Duodenal ulcers, which account for 8.
Most peptic ulcers not caused by H. Peptic ulcers are painful sores in the lining of the. The most common symptom of a peptic ulcer is burning abdominal pain that extends from the navel. There are three types of peptic ulcers: gastric. Both stomach and duodenal ulcers are sometimes referred to as peptic ulcers. Here the term “stomach ulcer” will be used, although the information applies equally to duodenal ulcers. Overview of Peptic Ulcer Disease. Peptic ulcers are typically named for their anatomical location. Untreated peptic ulcers may cause other health problems. If they become too deep, they can break through your stomach. Ulcers can also keep food from going through your stomach.
Ulcers and Gastrointestinal Bleeding: Protecting Your Health. Science has recognized that there are two types of. Different Types of Ulcers Explained. Most Common Types of Ulcers.
The symptoms of gastric and duodenal ulcer are similar and include a gnawing, burning ache and hungerlike pain in the mid- upper abdomen, usually experienced from one to three hours after meals and several hours after retiring. In the early 1. 98. Australian researchers, Barry Marshall and J. Robin Warren, challenged previous theories of ulcer development with evidence that ulcers could be caused by H.
This theory was greeted with skepticism because it was thought that no organism could live in the highly acidic conditions of the stomach and duodenum. Although the mechanism is not completely understood, this process causes the mucosal lining to break down.
In its weakened condition the lining cannot withstand the corrosive effects of gastric acid, and an ulcer can form. Infection with H. Among those who suffer from peptic ulcers, as many as 9. H. Evidence also exists that untreated H. The recommended treatments for H. Bismuth subsalicylate may also be used to protect the lining of the stomach from acid. Most peptic ulcers not caused by H.
Withdrawal of NSAID treatment usually allows the ulcer to heal, but if this is not possible the ulcer can be managed with the H2 blockers cimetidine and ranitidine (marketed as Tagamet. A small proportion of peptic ulcers results from the Zollinger- Ellison syndrome, an uncommon disease associated with a tumour of the duodenum or pancreas that causes an increase in gastric acid secretion.
Cigarette smoking has been found to have an adverse effect on peptic ulcers, slowing healing and promoting recurrence. Complications of ulcers include bleeding, perforation of the abdominal wall, and obstruction of the gastrointestinal tract.